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Just wondering how practical this test would be to a MS patient?
I included it in a blood test once as I was feeling extra rough that time and the resulting number was low so as I saw no correlation between how I felt and the blood result I have not bothered doing it again.
Warning - geek time coming up :geek: :oops: :geek: :lol: :geek:
C-reactive protein (CRP) is often one of the blood tests done as part of the "screening" tests done during MS diagnosis. It tends to be a marker of significant inflammation, and usually done in conjunction with Erythrocyte Sedimentation Rate (ESR), which is also another inflammatory marker. There is also a test for High Sensitivity CRP, which is more accurate. They can all be used for identifying/monitoring inflammation levels in a number of conditions/diseases. The following website is very useful for getting a basic understanding of blood tests (link is to the USA site, this seems to contain more comprehensive information than the equivalent Labtestsonline sites in other countries). Some of the information provided is not entirely comprehensive e.g. the HS-CRP test makes no mention of using it for immune conditions, but it is used for these by some medical practitioners. There are not many reference ranges quoted on the websites as different labs and countries use different measures and reference ranges (e.g. in UK B12 is pg/ml and in Aus nmol/L, same sort of thing for Vit D3). In Australia the level for CRP is meant to be <5mg/L, HS-CRP the same, and ESR <20 mm/hr.

How you feel does not necessarily have any correlation with actual test results - you might feel really good and still have abnormal results, and vice versa. Note that if you are on one of the interferons and taking NSAIDs to counter the flu-like side effects this will generally result in lower inflammatory marker test results than if you were not taking NSAIDs, so test results are not always a true indicator of what is going on.

http://labtestsonline.org/
http://labtestsonline.org/understanding ... /tab/test/
http://labtestsonline.org/understanding ... /tab/test/
http://labtestsonline.org/understanding ... /tab/test/

There is also a useful chart on Wikipedia, although it is quite confusing to work things out on it sometimes.
http://en.wikipedia.org/wiki/Reference_ ... lood_tests
My husband got sent to get his CRP levels on his last blood work so I looked it up a while ago.

Based on this paper I found It would seem that in MS the change over time for the particular individual does correlate with indication of relapse or remission and higher levels did correlate with faster progression. However all the levels were still within normal ranges.

http://www.ncbi.nlm.nih.gov/pubmed/16009907

So it could be a good way to monitor this indicator for what happens over time. It will certainly give you an indication of systemic inflammation but NOT inflammation in the CNS. I guess I would call this one "it can't hurt but one test will tell you very little in itself".Subsequent tests would let you "keep an eye" on keeping your levels steady.

However I am much like TigerT a geek deep down inside!

Best of luck
V.
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