As far as I am aware, everyone can feel certain symptoms which can mimic MS symptoms, but not be related to ms in any way. I have read many accounts from people who have sworn they have MS after experiencing pins & needles/numbness along with brain fog or other cognitive issues, but have shown no lesions or evidence of MS on multiple MRI scans - so I think the answer is 'Yes' you can experience symptoms without lesions.
If you don't mind me asking, what symptoms have you recently been having?
I was diagnosed around 9 months ago after my first known major relapse, and for the last 2-3 months I have had a fading feeling of weakness in the lower back/upper leg, which sometimes feels like the onset of a relapse, but never progresses. I have reasoned that this is down to maybe a little bit of wastage in that area, or an echo from my relapse - but I'm really unsure, although I am confident that it is not the onset of a relapse.