Interesting thread and really disappointing to read what the US and Canadian governments are doing by spreading propaganda against vitamin D. On the other end of the spectrum in Switzerland (where I am located), I have just discovered through my GP that vitamin D therapy is encouraged and recommended for ms patients and some cancer patients. In fact, doctors should recommend an initial check of the vitamin D3 level, followed by a mega-dose of 300,000 IU to get a minimum level of 60ug/L (about 150 ng/mL)... In certain cases, such as MS, the target level is a bit higher and the initial dose can go as high as 600,000 IU. This all sounds very familiar and virtually identical to what George has recommended in the OMS program. As for maintaining the blood level, the recommendation is a 300,000 IU dose every 3 months or 45,000 IU weekly. The dose is in a liquid form and very easy and inexpensive to get in Switzerland. This is a pretty new program in Switzerland and represents a huge departure from previous recommendations. I hope this type of program will become the norm in the future and not the exception!