Researchers at Buffalo University have a strong background in MS research, and have been looking at a variety of important potential modifiers of disease progression over recent years. They have previously noted a connection between high cholesterol and disability in people with MS (view full article), and on this occasion studied a group of people with their first demyelinating event who were part of one of the drug trials, looking at their lipid (fat) profile and brain lesion development on MRI scanning.
Their study, published in the Journal of Neurology, Neurosurgery and Psychiatry, a very high-ranking neurology journal, found that worse lipid profiles, with high cholesterol levels, were associated with worse MRI measures of lesion activity, that is more brain lesions.
Their final statement in the paper is: "Early intervention with dietary, exercise and lifestyle modifications shown to reduce cholesterol may be useful for managing MS progression but require further study". These modifications are exactly what we have long promoted here at OMS: reducing saturated fat to <15g/day, smoking cessation, regular exercise, stress reduction, and so on. It is a slow process, but the research is starting to catch up with our recommendations.