Researchers at La Trobe University in Victoria, Australia have studied the effects of progressive resistance training using a tailored gym program with weight training for the lower limbs for people with MS.
While failing to show that this improved walking, it did improve muscle performance, but also quality of life, and reduced fatigue. Importantly, the benefits for quality of life and fatigue disappeared once the training stopped.
It is clear that exercise only helps if you do it! These simple, effective self-help interventions are often forgotten when managing people with MS; a drug-only approach to MS is not good medicine.