What’s the evidence that lifestyle specifically impacts people with MS?

[1] Barker et al (2018), Self-management capability in patients with long-term conditions is associated with reduced healthcare utilisation across a whole health economy: cross-sectional analysis of electronic health records, http://dx.doi.org/10.1136/bmjqs-2017-007635

[2] European Committee for Treatment & Research in Multiple Sclerosis, October 13-15, 2021, p144

[3] Sorensen P and Magyari M, ‘Comorbidity in Multiple Sclerosis’, Front. Neurol., 21 August 2020 | https://doi.org/10.3389/fneur.2020.00851

[4] Salter A, et al Comorbidity is associated with disease activity in MS
Findings from the CombiRx trial, Neurology Aug 2020, 95 (5) e446-e456; DOI: 10.1212/WNL.0000000000010024

[5] MS Brain Health: Why manage comorbidities? accessed https://www.msbrainhealth.org/healthcare-professionals/why-manage-comorbidities-in-people-with-multiple-sclerosis/

[6] Rodgers et al (2022), The impact of smoking cessation on multiple sclerosis progression’ ‘https://doi.org/10.1093/brain/awab385

[7] Proschinger, S et al. Fitness, physical activity, and exercise in multiple sclerosis: a systematic review on current evidence for interactions with disease activity and progression. J Neurol 269, 2922–2940 (2022). https://doi.org/10.1007/s00415-021-10935-6

[8] Tettey P, Simpson S, Taylor B, et alAn adverse lipid profile and increased levels of adiposity significantly predict clinical course after a first demyelinating eventJournal of Neurology, Neurosurgery & Psychiatry 2017;88:395-401.

[9] Mowry EM, Azevedo CJ, McCulloch CE, Okuda DT, Lincoln RR, Waubant E, Hauser SL, Pelletier D. Body mass index, but not vitamin D status, is associated with brain volume change in MS. Neurology. 2018 Dec 11;91(24):e2256-e2264. doi: 10.1212/WNL.0000000000006644. Epub 2018 Nov 14. PMID: 30429274; PMCID: PMC6329329.

[10] Salter A, Kowalec K, Fitzgerald KC, Cutter G, Marrie RA, 'Comorbidity is associated with disease activity in MS: Findings from the CombiRx trial', Neurology Aug 2020, 95 (5) e446-e456; DOI: 10.1212/WNL.0000000000010024

[11] Briggs FBS, Thompson NR, Conway DS. Prognostic factors of disability in relapsing remitting multiple sclerosis. Mult Scler Relat Disord. 2019 May;30:9-16. doi: 10.1016/j.msard.2019.01.045. Epub 2019 Jan 29. PMID: 30711764.

[12] Huppke B, Ellenberger D, Hummel H, Stark W, Röbl M, Gärtner J, Huppke P. Association of Obesity With Multiple Sclerosis Risk and Response to First-line Disease Modifying Drugs in Children. JAMA Neurol. 2019 Jul 15;76(10):1157–65. doi: 10.1001/jamaneurol.2019.1997. Epub ahead of print. PMID: 31305922; PMCID: PMC6632118.

[13] NICE (2022), Multiple sclerosis in adults: management, NICE guideline [NG220] https://www.nice.org.uk/guidance/ng220

[14] Neurology Academy (2022), Putting policy into practice; disease-modifying lifestyle https://neurologyacademy.org/articles/putting-policy-into-practice-disease-modifying-lifestyle

[15] Peel C (2021) Evidence for non-medical management in MS: optimised management and patient participation, BJNN https://doi.org/10.12968/bjnn.2021.17.Sup1.S31

[16] Asano, M. and Finlayson, M.L., 2014. Meta-analysis of three different types of fatigue management interventions for people with multiple sclerosis: exercise, education, and medication. Multiple sclerosis international, 2014

[17] Heine, M., van de Port, I., Rietberg, M.B., van Wegen, E.E. and Kwakkel, G., 2015. Exercise therapy for fatigue in multiple sclerosis. Cochrane database of systematic reviews, (9).

[18] Peters (2019), Self-efficacy and health-related quality of life: a cross-sectional study of primary care patients with multi-morbidity https://doi.org/10.1186/s12955-019-1103-3

[19] Barker et al (2018), Self-management capability in patients with long-term conditions is associated with reduced healthcare utilisation across a whole health economy: cross-sectional analysis of electronic health records, http://dx.doi.org/10.1136/bmjqs-2017-007635

[20] The Health Foundation (2011), Helping people help themselves. A review of the evidence considering whether it is worthwhile to support self-management https://www.health.org.uk/sites/default/files/HelpingPeopleHelpThemselv…